Antimicrobial Peptides and Human Disease (Current Topics in by William Shafer

By William Shafer

Microbes are in our midst quickly after start. fortunately, the variety of risk free (and usually worthy) microbes some distance outnumber those who might do us damage. Our skill to ward-off pathogens in the environment, together with those who can colonize our external and/or inside surfaces, will depend on the integrative motion of the innate and adaptive immunity structures. This quantity of CTMI, entitled Antimicrobial Peptides and Human disorder, is devoted to the position of antimicrobial peptides (AMPs) within the innate host protection method of homo sapiens.

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2000a). Immunomodulatory Properties of Defensins and Cathelicidins 41 Collectively, these data indicate that neutrophil granules contain important chemotactic factors which promote the infiltration of cells of both the innate and adaptive immune responses. The β-defensins HBD1 and HBD2 are chemoattractants for immature dendritic cells and memory T, cells with peak activities occurring at 1 µg/ml (Yang et al. 1999). These activities are mediated through the chemokine receptor CCR6, which also binds the chemokine LARC.

Porter EM, Bevins CL, Ghosh D, Ganz T (2002) The multifaceted Paneth cell. Cell Mol Life Sci 59:156–170 93. Quayle AJ, Porter EM, Nussbaum AA, Wang YM, Brabec C, Yip KP, Mok SC (1998) Gene expression, immunolocalization, and secretion of human defensin-5 in human female reproductive tract. Am J Pathol 152:1247–1258 94. Rice WG, Ganz T, Kinkade JM Jr, Selsted ME, Lehrer RI, Parmley RT (1987) Defensin-rich dense granules of human neutrophils. Blood 70:757–765 95. Rodriguez-Jimenez FJ, Krause A, Schulz S, Forssmann WG, Conejo-Garcia JR, Schreeb R, Motzkus D (2003) Distribution of new human beta-defensin genes clustered on chromosome 20 in functionally different segments of epididymis.

2 Host Defence Peptides in the Adaptive Immune Response . . . . . . 46 Adjuvant Activity . . . . . . . . . . . . . . . . . . . . 46 Mechanisms . . . . . . . . . . . . . . . . . . . . . . 50 4 Conclusion . . . . . . . . . . . . . . . . . . . . . . 53 References . . . . . . . . . . . . . . . . . . . . . . . . . 55 Abstract Host defence peptides are a conserved component of the innate immune response in all complex life forms.

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